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Despite its therapeutic potential, current evidence is limited by methodological gaps, preclinical inconsistencies and weak clinical evidence (no large-scale randomized controlled trials [RCTs])

it organizes into functional structure rather than disorganized scar tissue

A study conducted at the University College London Hospital found that most men who used VED twice a day experienced improvements in penile length, curvature, and pain after 12 weeks

Cautious use of parenteral cyanocobalamin is also recommended in patients with renal impairment, including premature neonates, because of the possibility of greater aluminum accumulation, which may cause central nervous system and bone toxicity